Correction: DNA microarray analysis of rheumatoid arthritis susceptibility genes identified by genome-wide association studies
نویسندگان
چکیده
*Correspondence: [email protected] 1Graduate School of Frontier Bioscience, Osaka University, 1-3 Yamada-Oka, Suita-City, Osaka 565-0871, Japan Full list of author information is available at the end of the article doi:10.1186/ar3023 Cite this article as: Sugino H, et al.: Correction: DNA microarray analysis of rheumatoid arthritis susceptibility genes identifi ed by genome-wide association studies. Arthritis Research & Therapy 2010, 12:403.
منابع مشابه
DNA microarray analysis of rheumatoid arthritis susceptibility genes identified by genome-wide association studies
Vyse described the genetics of rheumatic disease [1]. In the past several years, genome-wide association studies (GWAS) have led to the identifi cation of six high-risk rheumatoid arthritis (RA) susceptibility genes – namely, CD244, PADI4, SLC22A2, PTPN22, CTLA4, and STAT4 (summarized in [2]). In vitro studies using mutant alleles and cultured cells have revealed the individual up-regulation of...
متن کاملPredicting CpG Islands and DNA Methlation in the Cow Genome Using DNA Microarray Meta-Analysis and Genome Wide Scanning
DNA methylation is a type of epigenetic changes that directly affects DNA. In mammals, DNA methylation is essential for fetal development and stem cell differentiation and this phenomenon essentially occurs within the CpG islands. In this study, two methods were used to study the DNA methylation profile of cow genome. In the first method, the DNA methylation profile of the differentially expres...
متن کاملIdentification of novel putative rheumatoid arthritis susceptibility genes via analysis of rare variants
Established loci for rheumatoid arthritis (RA), including HLA-DRB1 and PTPN22, do not fully account for the genetic component of susceptibility to the disease. One possible source of as yet undiscovered susceptibility genes are those mediated through effects of rare variants. We present a novel method for gene-based genome-wide scans of whole-genome association (WGA) data to identify accumulati...
متن کاملReplication of recently identified associated single-nucleotide polymorphisms from six autoimmune diseases in Genetic Analysis Workshop 16 rheumatoid arthritis data
Many autoimmune diseases share similar underlying pathology and have a tendency to cluster within families, giving rise to the concept of shared susceptibility genes among them. In the Genetic Analysis Workshop 16 rheumatoid arthritis (RA) data we sought to replicate the genetic association between single-nucleotide polymorphisms (SNPs) identified in recent genome-wide association studies (GWAS...
متن کاملOverlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis
BACKGROUND Genome-wide association studies (GWAS) have been extremely successful in the search for susceptibility risk factors for complex genetic autoimmune diseases. As more studies are published, evidence is emerging of considerable overlap of loci between these diseases. In juvenile idiopathic arthritis (JIA), another complex genetic autoimmune disease, the strategy of using information fro...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 12 شماره
صفحات -
تاریخ انتشار 2010